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Symbol
Name
ID
Esr2
estrogen receptor 2 (beta)
MGI:109392
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Pericarditis
Premature coronary artery atherosclerosis
Vasculitis
Elevated diastolic blood pressure
Elevated systolic blood pressure
Hypertension
Raynaud phenomenon
Sudden cardiac death
Myocardial infarction
Congestive heart failure
Abnormality of the hepatic vasculature
Lymphadenopathy
Hepatosplenomegaly
Disease(s) Associated with ESR2
coronary artery disease
Graves' disease
pre-eclampsia
rheumatoid arthritis
systemic lupus erythematosus

Mouse Phenotypes
cardiovascular system phenotype
abnormal vascular smooth muscle morphology
abnormal myocardial fiber morphology
abnormal intercalated disk morphology
increased myocardial fiber size
increased heart weight
enlarged heart
cardiac hypertrophy
dilated heart ventricle
abnormal response of heart to induced stress
abnormal response to cardiac infarction
increased systemic arterial blood pressure
abnormal vascular smooth muscle physiology
increased vasoconstriction
increased vasodilation
Availability Mouse Genotype
Esr2tm1.2Pcn/Esr2tm1.2Pcn *
Esr2tm1Unc/Esr2tm1Unc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory